Laboratory Investigations in Molecular Biology Steven A. Williams, Barton E. Slatko, John R. McCarrey Laboratory Investigations in Molecular Biology presents well-tested protocols in molecular biology that are commonly used in currently active research labs. Because of the molecular organization and flexible design of the manual, laboratory courses can be assembled in a way that is ideal for science professionals, graduate students, undergraduate students, and even advanced-placement high school students. The experiments are designed to guide students through realistic research projects and to provide them with instruction in methods and approaches that can be immediately translated into research projects conducted in modern research laboratories. The manual is also useful as a laboratory "bench reference". Although these experiments have been conducted and optimized over 20 years of teaching at the New England Biolabs Molecular Biology Summer Workshops, they are real research projects, not "canned" experiments. Based on extensive teaching experience using these protocols, the authors have found that conducting these experiments as described serves to effectively instruct students and science professionals in the basic methods of molecular biology. Reagent kits that provide quality-tested, pre-packaged reagents to ensure the successful application of the protocols described in the manual are also available.